Danny Tickle was sent off as 19-times winners Wigan Warriors reached the Ladbrokes Challenge Cup quarter-finals with a 28-10 victory over Hull KR.
Tickle reacted with an apparent punch after clashing with Warriors second row John Bateman in the final set before the interval hooter.
Josh Woods set Wigan on the way to the last eight with an 11th-minute try but Rovers responded through Woods’ former Swinton half back partner Chris Atkin.
Liam Marshall restored Wigan’s lead and the tie seemingly tipped the visitors' way with the flashpoint between Tickle and Bateman.
Instead Rovers hit back after the re-start as Junior Vaivai touched down after 50 minutes, with Ryan Shaw's penalty levelling the scores.
Sam Tomkins went over after 62 minutes and Wigan finally made their extra man pay with late tries from Tony Clubb and Tom Davies.
Wigan coach Shaun Wane said: “It is always tough when we come here. Hull KR are under the pump with injuries and teams, when they are under pressure like that, they fire up.
“That’s what they did. When the opposition get a man sent-off it doesn’t always work your way.
“But we have a lot of competitors like Sam Tomkins and John Bateman who managed the game towards the end.
“Hull KR still had some quality players out there even though they were busted. They showed lots of character.
Tim Sheens confirms to press that’s it’s a possible ACL injury for Robbie Mulhern but no confirmation yet. We await news during the week but fingers crossed.— Hull Kingston Rovers (@hullkrofficial) May 13, 2018
“You just have to be patient and show them respect. We gave some terrible penalties away and our error rate was poor
“There were just too many pressure releases but we are in the next round which is what we wanted.”
Hull KR coach Tim Sheens added: “To get the penalty off it and lose someone on a red card hurts, doesn’t it?"
Rovers also added three players to their lengthy injury list: Robbie Mulhern (suspected anterior cruciate ligament), Mose Masoe (ankle) and James Greenwood (concussion).
“Losing Danny didn’t help because we had to adjust a whole heap of things at half-time,” added Sheens.
“But we hung in there for the first part of the second half. The last 15 minutes Wigan got away from us but everyone was exhausted."